| Title |
Race, Income, and Disease Outcomes in Juvenile Dermatomyositis
|
|---|---|
| Published in |
Journal of Pediatrics, March 2017
|
| DOI | 10.1016/j.jpeds.2017.01.046 |
| Pubmed ID | |
| Authors |
Kathryn Phillippi, Mark Hoeltzel, Angela Byun Robinson, Susan Kim, Childhood Arthritis and Rheumatology Research Alliance Legacy Registry Investigators, Leslie S. Abramson, Eleanor S. Anderson, Mara L. Becker, Heather Benham, Timothy Beukelman, Peter R. Blier, Hermine I. Brunner, Joni Dean, Fatma Dedeoglu, Brian M. Feldman, Polly I. Ferguson, Donald P. Goldsmith, Beth S. Gottlieb, Thomas B. Graham, Thomas A. Griffin, Hilary M. Haftel, Gloria C. Higgins, J.R. Hollister, Joyce J. Hsu, Anna Huttenlocher, Norman T. Ilowite, Lisa F. Imundo, Rita S. Jerath, Lawrence K. Jung, Philip J. Kahn, Daniel J. Kingsbury, Kristin E. Klein, Marisa S. Klein-Gitelman, Sivia K. Lapidus, Thomas J.A. Lehman, Carol B. Lindsley, Michael A. Malloy, Deborah K. McCurdy, Eyal Muscal, Judyann C. Olson, Kathleen M. O'Neil, Karen Onel, Sampath Prahalad, Marilynn G. Punaro, C. Egla Rabinovich, Ann M. Reed, Sarah Ringold, Mary Ellen Riordan, Angela B. Robinson, Deborah Rothman, Natasha M. Ruth, Kenneth N. Schikler, Nora G. Singer, Steven Spalding, Reema H. Syed, Kathryn S. Torok, Jenna Tress, Richard K. Vehe, Emily Von Scheven, Lydia M. Walters, Jennifer E. Weiss, Pamela Weiss, Andrew J. White, Jennifer M. Woo, Ali Yalcindag, Lawrence S. Zemel |
| Abstract |
To determine the relationships among race, income, and disease outcomes in children with juvenile dermatomyositis (JDM). Data from 438 subjects with JDM enrolled in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Legacy Registry were analyzed. Demographic data included age, sex, race, annual family income, and insurance status. Clinical outcomes included muscle strength, presence of rash, calcinosis, weakness, physical function, and quality of life measures. Disease outcomes were compared based on race and income. Minority subjects were significantly more likely to have low annual family income and significantly worse scores on measures of physical function, disease activity, and quality of life measures. Subjects with lower annual family income had worse scores on measures of physical function, disease activity, and quality of life scores, as well as weakness. Black subjects were more likely to have calcinosis. Despite these differences in outcome measures, there were no significant differences among the racial groups in time to diagnosis or duration of disease. Using calcinosis as a marker of disease morbidity, black race, annual family income <$50?000 per year, negative antinuclear antibody, and delay in diagnosis >12 months were associated with calcinosis. Minority race and lower family income are associated with worse morbidity and outcomes in subjects with JDM. Calcinosis was more common in black subjects. Further studies are needed to examine these associations in more detail, to support efforts to address health disparities in subjects with JDM and improve disease outcomes. |
Login to access the Attention Digest and the Sentiment Analysis related to this output.
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 29% |
| Spain | 1 | 14% |
| Unknown | 4 | 57% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 43% |
| Science communicators (journalists, bloggers, editors) | 2 | 29% |
| Scientists | 1 | 14% |
| Practitioners (doctors, other healthcare professionals) | 1 | 14% |
Mendeley demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 72 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 11 | 15% |
| Student > Master | 8 | 11% |
| Student > Bachelor | 7 | 10% |
| Other | 5 | 7% |
| Student > Doctoral Student | 5 | 7% |
| Other | 13 | 18% |
| Unknown | 23 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 23 | 32% |
| Nursing and Health Professions | 6 | 8% |
| Agricultural and Biological Sciences | 4 | 6% |
| Immunology and Microbiology | 4 | 6% |
| Biochemistry, Genetics and Molecular Biology | 2 | 3% |
| Other | 5 | 7% |
| Unknown | 28 | 39% |