RP @mndaus-research.bsky.social: Rethinking phase 2 trials in amyotrophic lateral sclerosis academic.oup.com/brain/articl... Well-thought out discussion - basically if you want to run 6-month Phase 2 trials - use biomarkers for your go/no-go decision. …
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17 Bluesky posts from 13 Bluesky users, with an upper bound of 3,290 followers.
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Rethinking phase 2 trials in amyotrophic lateral sclerosis academic.oup.com/brain/articl... Well-thought out discussion - basically if you want to run 6-month Phase 2 trials - use biomarkers for your go/no-go decision. If you want to use ALSFRS-R - you…
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Well, this is upsetting. But no worries; we’re only dying out here. #ALS #MND https://bsky.app/profile/did:plc:ioatghzqu5kmyphyou32rmuw/post/3lcxjsqc2tc2x
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RP @rpavaneijk.bsky.social: New paper to reflect on the main challenges in phase 2 #ALS #MND trials. Key issues relate too short study durations, reliance on the wrong outcome measures, absence of biomarkers, statistical issues, over-interpretation of '…