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Involvement of GABAA Receptors in the Neuroprotective Effect of Theanine on Focal Cerebral Ischemia in Mice

Overview of attention for article published in Journal of Pharmacological Sciences, October 2007
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#9 of 1,610)
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

Mentioned by

news
3 news outlets
blogs
1 blog
patent
4 patents
video
5 YouTube creators

Citations

dimensions_citation
70 Dimensions

Readers on

mendeley
46 Mendeley
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Title
Involvement of GABAA Receptors in the Neuroprotective Effect of Theanine on Focal Cerebral Ischemia in Mice
Published in
Journal of Pharmacological Sciences, October 2007
DOI 10.1254/jphs.scz070901
Pubmed ID
Authors

Nobuaki Egashira, Kazuhide Hayakawa, Megumi Osajima, Kenichi Mishima, Katsunori Iwasaki, Ryozo Oishi, Michihiro Fujiwara

Abstract

We investigated the involvement of gamma-aminobutyric acid(A) (GABA(A)) receptors in the neuroprotective effect of gamma-glutamylethylamide (theanine), a component of Japanese green tea, following a 4-h middle cerebral artery (MCA) occlusion in mice. Theanine (1 mg/kg) reduced the size of the cerebral infarct and alterations of NeuN, GFAP, and Iba 1 expression levels at 24 h after MCA occlusion. This neuroprotective effect of theanine was prevented by bicuculline (GABA(A)-receptor antagonist, 10 mg/kg) but not 3-mercaptopropionic acid (glutamate decarboxylase inhibitor). These results suggest that the neuroprotective effect of theanine is mediated, at least in part, by GABA(A) receptors.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 2%
Unknown 45 98%

Demographic breakdown

Readers by professional status Count As %
Other 8 17%
Researcher 8 17%
Student > Bachelor 4 9%
Student > Ph. D. Student 4 9%
Student > Master 4 9%
Other 7 15%
Unknown 11 24%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 15%
Pharmacology, Toxicology and Pharmaceutical Science 6 13%
Neuroscience 5 11%
Medicine and Dentistry 4 9%
Nursing and Health Professions 3 7%
Other 9 20%
Unknown 12 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 40. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 October 2023.
All research outputs
#1,029,090
of 25,374,917 outputs
Outputs from Journal of Pharmacological Sciences
#9
of 1,610 outputs
Outputs of similar age
#1,788
of 84,711 outputs
Outputs of similar age from Journal of Pharmacological Sciences
#1
of 12 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,610 research outputs from this source. They receive a mean Attention Score of 3.9. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 84,711 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.