Ring splitting prevents the loading of defective DNA replication machinery
npj Science of Learning Community,
DNA replication must be faithful to avoid errors accumulating in daughter cells that can lead to diseases such as cancer. We…
Regulation of replication origin licensing by ORC phosphorylation reveals a two-step mechanism for Mcm2-7 ring closing
Overview of attention for article published in Proceedings of the National Academy of Sciences of the United States of America, July 2023
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