Infection-Triggered Familial or Recurrent Cases of Acute Necrotizing Encephalopathy Caused by Mutations in a Component of the Nuclear Pore, RANBP2

RT @aneinternationa: "Increased serum and CSF levels of IL-6 and TNF-α have been reported in children with ANE, leading to the prevailing h…

"Increased serum and CSF levels of IL-6 and TNF-α have been reported in children with ANE, leading to the prevailing hypothesis of a “cytokine storm” as part of the pathogenic mechanism. Morbidity and mortality are high". https://t.co/CZV0Sy0blL #ANEandUs…

@VirusesImmunity @aneinternationa @CDCFlu @Immunisation_Au @Immunize_USA @virusninja @AmerSocVirol @VishwaDeepDixi1 @DrEmilyGoldberg @Cornymel @PaulBieniasz @jonykipnis @KaminskiMed Interesting! The RANBP2 variant (het) is compelling. Inflammation-induc…