| Title |
Methods in Nutrition Science: The Bone Remodeling Transient: Interpreting Interventions Involving Bone-related Nutrients
|
|---|---|
| Published in |
Nutrition Reviews, April 2009
|
| DOI | 10.1111/j.1753-4887.2001.tb06957.x |
| Pubmed ID | |
| Authors | |
| Abstract |
The bone remodeling transient is a temporary alteration in the balance between bone formation and bone resorption, brought about by any agency that affects bone remodeling. Ascertaining the steady state effect of an intervention requires factoring the component of the change due to the transient out of the total bony response. Since parathyroid hormone (PTH) is the principal regulator of the quantity of remodeling activity, and since calcium intake influences PTH secretion, it follows that altering calcium intake will always induce a remodeling transient. Worked examples from three published calcium intervention studies are presented, and the errors that can be made by ignoring the transient and simply measuring change in bone mass across treatment are described. |
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Mendeley demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 27 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 6 | 22% |
| Student > Bachelor | 5 | 19% |
| Student > Master | 4 | 15% |
| Other | 2 | 7% |
| Student > Doctoral Student | 2 | 7% |
| Other | 3 | 11% |
| Unknown | 5 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 6 | 22% |
| Medicine and Dentistry | 6 | 22% |
| Nursing and Health Professions | 4 | 15% |
| Biochemistry, Genetics and Molecular Biology | 2 | 7% |
| Social Sciences | 1 | 4% |
| Other | 2 | 7% |
| Unknown | 6 | 22% |