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Structural and functional brain network correlates of depressive symptoms in premanifest Huntington's disease

Overview of attention for article published in Human Brain Mapping, March 2017
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)
  • High Attention Score compared to outputs of the same age and source (81st percentile)

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24 X users
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109 Mendeley
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Article details
Title
Structural and functional brain network correlates of depressive symptoms in premanifest Huntington's disease
Published in
Human Brain Mapping, March 2017
DOI 10.1002/hbm.23527
Pubmed ID
Authors
Abstract

Depression is common in premanifest Huntington's disease (preHD) and results in significant morbidity. We sought to examine how variations in structural and functional brain networks relate to depressive symptoms in premanifest HD and healthy controls. Brain networks were constructed using diffusion tractography (70 preHD and 81 controls) and resting state fMRI (92 preHD and 94 controls) data. A sub-network associated with depression was identified in a data-driven fashion and network-based statistics was used to investigate which specific connections correlated with depression scores. A replication analysis was then performed using data from a separate study. Correlations between depressive symptoms with increased functional connectivity and decreased structural connectivity were seen for connections in the default mode network (DMN) and basal ganglia in preHD. This study reveals specific connections in the DMN and basal ganglia that are associated with depressive symptoms in preHD. Hum Brain Mapp, 2017. © 2017 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc.

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X Demographics

X Demographics

The data shown below were collected from the profiles of 24 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley demographics

Mendeley demographics

The data shown below were compiled from readership statistics for 109 Mendeley readers of this research output. Click here to see the associated Mendeley record.
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Geographical breakdown

Geographical breakdown
Country Count As %
Germany 1 <1%
Unknown 108 99%

Demographic breakdown

Readers by professional status
Readers by professional status Count As %
Student > Ph. D. Student 19 17%
Researcher 18 17%
Student > Bachelor 10 9%
Student > Master 9 8%
Student > Doctoral Student 8 7%
Other 16 15%
Unknown 29 27%
Readers by discipline
Readers by discipline Count As %
Neuroscience 32 29%
Medicine and Dentistry 15 14%
Psychology 9 8%
Biochemistry, Genetics and Molecular Biology 3 3%
Philosophy 1 <1%
Other 9 8%
Unknown 40 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 July 2017.
All research outputs
#2,982,694
of 34,150,266 outputs
Outputs from Human Brain Mapping
#631
of 4,968 outputs
Outputs of similar age
#42,917
of 349,977 outputs
Outputs of similar age from Human Brain Mapping
#17
of 92 outputs
Altmetric has tracked 34,150,266 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,968 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.2. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 349,977 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 92 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.