Binding‐Site Purification of Actives (B‐SPA) Enables Efficient Large‐Scale Progression of Fragment Hits by Combining Multi‐Step Array Synthesis With HT Crystallography

New Paper from I04-1 in @angew_chem https://t.co/xkcKAKAJcv (https://t.co/He9Kh3luda)

RT @angew_chem: Binding-Site Purification of Actives (B-SPA) Enables Efficient Large-Scale Progression of Fragment Hits by Combining Multi-…

Binding-Site Purification of Actives (B-SPA) Enables Efficient Large-Scale Progression of Fragment Hits by Combining Multi-Step Array Synthesis With HT Crystallography (Frank von Delft and co-workers) @JSpencerlab @SussexDDC @DiamondLightSou #openaccess …

🚨Binding-Site Purification of Actives—faster, greener, cheaper way to advance fragment hits! 🦾With robot chemistry, automated QC & HT crystallography, we skip purification & accelerate SAR! 🔗https://t.co/TvRLoRyUV3 @FrankvonDelft @philbiggin…