A new study shows that the nucleosome switch of HBV's cccDNA controls infection onset by regulating the Smc5/6 complex; understanding this mechanism could lead to novel therapies. PMID:39983728, Cell 2025, @Cell https://t.co/Oiex9tzX5U #AI #Pharma #BioM…
A study reveals that HBV primes infection by switching nucleosomes, launching viral X gene expression to degrade the Smc5/6 complex. This uncovers cccDNA's critical role in chronic HBV pathogenesis. PMID:39983728, Cell 2025, @Cell https://t.co/aKqQNGIUm…
RT @vivrisca: It was a privilege to work with @Yael_David__ and @RobSchwartzLab on this project investigating how chromatin regulates early…
RT @RobSchwartzLab: Really excited to share our collaborative and new work on HBV with @Yael_David__ and @vivrisca revealing how HBV infect…