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Check out this newly published paper in LSA: STAT5B leukemic mutations, altering SH2 tyrosine 665, have opposing impacts on immune gene programs www.life-science-alliance.org/content/8/7/...
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219 followers
Germ-line activating and deactivating mutations of STAT5b, part of the JAK-STAT signaling pathway, push the immune system and hematopoiesis in opposing directions, tuning systems either up or down www.life-science-alliance.org/content/8/7/...