Verapamil and its metabolite norverapamil inhibit the Mycobacterium tuberculosis MmpS5L5 efflux pump to increase bedaquiline activity

Overview of attention for article published in Proceedings of the National Academy of Sciences of the United States of America, April 2025

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HMN 2025: How to establish tuberculosis drug-resistance inhibitor and map full construction of key bacterial pump

Health Medicine Network, 10 Jun 2025

Cryo-EM construction of the MmpL5-MmpS5-AcpM complicated from Mycobacterium tuberculosis. Credit: Nature Communications (2025).

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