Title |
Meningococcemia due to the 2000 Hajj-Associated Outbreak Strain (Serogroup W-135 ST-11) with Immunoreactive Complications
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Published in |
Japanese Journal of Infectious Diseases, January 2013
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DOI | 10.7883/yoken.66.443 |
Pubmed ID | |
Authors |
Kei Yamamoto, Yasuyuki Kato, Takuma Shindo, Mugen Ujiie, Nozomi Takeshita, Shuzo Kanagawa, Junwa Kunimatsu, Yuiichi Tamori, Toshikazu Kano, Rumi Okuno, Hideyuki Takahashi, Norio Ohmagari |
Abstract |
We present the first reported case of systemic infection with Neisseria meningitidis serogroup W-135 sequence type (ST)-11 in Japan. A 44-year-old woman presented with high fever, sore throat, and fatigue and was diagnosed with N. meningitidis bacteremia. The causative strain was identified as serogroup W-135 ST-11 by polymerase chain reaction and multilocus sequence typing. Approximately 1 month after treatment, she developed high fever, dyspnea, chest pain, and shoulder pain due to pericarditis, polyarthritis, and tenosynovitis, which are all relatively common immunoreactive complications of W-135 ST-11 meningococcal infections. This causative strain was the same as that responsible for an outbreak of meningitis among Hajj pilgrims in 2000. The strain is now found worldwide because it can attain a high carriage rate and has a long duration of carriage. We suspect that our patient's infection was acquired from an imported chronic carrier. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Japan | 1 | 5% |
Unknown | 19 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 6 | 30% |
Other | 3 | 15% |
Student > Doctoral Student | 2 | 10% |
Student > Bachelor | 2 | 10% |
Lecturer | 1 | 5% |
Other | 2 | 10% |
Unknown | 4 | 20% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 8 | 40% |
Biochemistry, Genetics and Molecular Biology | 2 | 10% |
Nursing and Health Professions | 2 | 10% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 5% |
Immunology and Microbiology | 1 | 5% |
Other | 1 | 5% |
Unknown | 5 | 25% |