329 followers
血液、尿バイオマーカーと腎イベント、死亡イベントの予測精度の研究?苦手な分野である。 前提として、現在もCKDのリスク評価でKFREを超えるものはないようだ。血清、尿中バイオマーカーの組み合わせを評価した論文。 https://t.co/Q4tiygDAF4
410 followers
In 2,884 CKD pts, biomarker panels predicted outcomes. • Kidney failure: sTNFR1, sCD40, urinary COL1A1 (C-index 0.86) • Mortality: hs-cTnT, NT-proBNP, suPAR (0.80) Comparable to eGFR+UACR but add mechanistic insight. #CKD #biomarkers #nephrology https://t…
410 followers
In 2,884 CKD pts, biomarker panels predicted outcomes. • Kidney failure: sTNFR1, sCD40, urinary COL1A1 (C-index 0.86) • Mortality: hs-cTnT, NT-proBNP, suPAR (0.80) Comparable to eGFR+UACR but add mechanistic insight. #CKD #biomarkers #nephrology https://t…
410 followers
In 2,884 CKD pts, biomarker panels predicted kidney failure (C=0.86) & mortality (0.80), near eGFR+UACR (0.90/0.80). Insightful biology, limited added prediction. #proteomics #biomarker #diagnostics https://t.co/893Z5Nrpmy