Somatic CRISPR tumorigenesis and multiomic analysis reveal a pentose phosphate pathway disruption vulnerability in MPNSTs

Overview of attention for article published in Science Advances, August 2025

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In the top 5% of all research outputs scored by Altmetric
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The authors included RRIDs in their in Science Advances paper! Thanks for making your methods matter! #BetterScience #methodsmatter #accelerateopenscience

Congratulations to Dr. Eric Taylor, his lab, and collaborators on their new publication “Somatic CRISPR tumorigenesis and multiomic analysis reveal a pentose phosphate pathway disruption vulnerability in MPNSTs” published in Science Advances. doi.org/10.1…

Researchers have identified a critical metabolic pathway in Malignant Peripheral Nerve Sheath Tumor cells, offering a potential new target for therapies against this aggressive childhood cancer. doi.org/g9xhhb

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