Title |
Identification of Two novel reassortant avian influenza a (H5N6) viruses in whooper swans in Korea, 2016
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Published in |
Virology Journal, March 2017
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DOI | 10.1186/s12985-017-0731-7 |
Pubmed ID | |
Authors |
Jipseol Jeong, Chanjin Woo, Hon S. Ip, Injung An, Youngsik Kim, Kwanghee Lee, Seong-Deok Jo, Kidong Son, Saemi Lee, Jae-Ku Oem, Seung-Jun Wang, Yongkwan Kim, Jeonghwa Shin, Jonathan Sleeman, Weonhwa Jheong |
Abstract |
On November 20, 2016 two novel strains of H5N6 highly pathogenic avian influenza virus (HPAIVs) were isolated from three whooper swans (Cygnus cygnus) at Gangjin Bay in South Jeolla province, South Korea. Identification of HPAIVs in wild birds is significant as there is a potential risk of transmission of these viruses to poultry and humans. Phylogenetic analysis revealed that Gangjin H5N6 viruses classified into Asian H5 clade 2.3.4.4 lineage and were distinguishable from H5N8 and H5N1 HPAIVs previously isolated in Korea. With the exception of the polymerase acidic (PA) gene, the viruses were most closely related to A/duck/Guangdong/01.01SZSGXJK005-Y/2016 (H5N6) (98.90 ~ 99.74%). The PA genes of the two novel Gangjin H5N6 viruses were most closely related to AIV isolates previously characterized from Korea, A/hooded crane/Korea/1176/2016 (H1N1) (99.16%) and A/environment/Korea/W133/2006 (H7N7) (98.65%). The lack of more recent viruses to A/environment/Korea/W133/2006 (H7N7) indicates the need for analysis of recent wild bird AIVs isolated in Korea because they might provide further clues as to the origin of these novel reassortant H5N6 viruses. Although research on the origins and epidemiology of these infections is ongoing, the most likely route of infection for the whooper swans was through direct or indirect contact with reassortant viruses shed by migratory wild birds in Korea. As H5N6 HPAIVs can potentially be transmitted to poultry and humans, continuous monitoring of AIVs among wild birds will help to mitigate this risk. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 3 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 67% |
Science communicators (journalists, bloggers, editors) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 26 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 7 | 27% |
Student > Master | 4 | 15% |
Other | 2 | 8% |
Student > Bachelor | 2 | 8% |
Librarian | 2 | 8% |
Other | 3 | 12% |
Unknown | 6 | 23% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 5 | 19% |
Veterinary Science and Veterinary Medicine | 3 | 12% |
Medicine and Dentistry | 3 | 12% |
Immunology and Microbiology | 3 | 12% |
Biochemistry, Genetics and Molecular Biology | 1 | 4% |
Other | 4 | 15% |
Unknown | 7 | 27% |