RP @molbioevol.bsky.social: The December cover of Molecular Biology and Evolution features the work of Chiu et al., who showed that later-evolving strains of SARS-CoV-2 acquired infectivity towards cultivated cells expressing New World monkey ACE2. 🔗 do…
The December cover of Molecular Biology and Evolution features the work of Chiu et al., who showed that later-evolving strains of SARS-CoV-2 acquired infectivity towards cultivated cells expressing New World monkey ACE2. 🔗 doi.org/10.1093/molbev/msaf281…
Chiu et al. used assayed cells expressing New World monkey ACE2 to show that later-evolving strains of SARS-CoV-2 acquired infectivity. Human-driven evolution of viral cells enhanced the potential for human-to-non-human transmission. 🔗 doi.org/10.1093/m…
RP @johnjxw.bsky.social: Later SARS-CoV-2 viruses in humans evolved the ability to use New World monkey ACE2, and recombination seems to be able to sample more mutations for the spike gene to cross species barriers. doi.org/10.1093/molb...