We introduced domain-swapping as a new strategy for de novo design. By scaffolding off-the-shelf EY, our fav photocatalyst with nM high affinity and fine-tuned properties, we enabled genetically encodable multiscale proximity labeling and mapped the nei…
New #ARTNetPublication introduces MultiMap, a temporal photoproximity labeling approach to track dynamic EGFR interaction neighborhoods in real time. pubmed.ncbi.nlm.nih.gov/41254216/
New #ARTNetPublication: Using paired photoproximity labeling (PLP) workflows, researchers dynamically mapped EGFR signaling neighborhoods inside and outside cells, capturing interactome changes within minutes to hours after EGF stimulation. pubmed.ncbi…
RP @innovativegenomics.bsky.social: 🎺New paper alert🎺 Out now in Nature Chemical Biology from IGI's Jennifer Doudna (Doudna Lab) and collaborators: Temporal photoproximity labeling of ligand-activated EGFR neighborhoods using MultiMap Read here: https:…