RP @natrevdiseaseprimers.nature.com: Advances and innovations in recognition, diagnosis and treatment of Buruli ulcer, a necrotizing skin disease caused by Mycobacterium ulcerans infection, have greatly improved patient outcomes. https://www.nature.c...
Advances and innovations in recognition, diagnosis and treatment of Buruli ulcer, a necrotizing skin disease caused by Mycobacterium ulcerans infection, have greatly improved patient outcomes. https://www.nature.c...
Buruli ulcer progression is driven by mycolactone from M. ulcerans, which inhibits the Sec61 protein complex, blocking protein translocation into the endoplasmic reticulum, leading to apoptosis, immune suppression and vascular dysfunction. https://www.n…
Buruli ulcer has been reported in at least 33 countries and, in 2024, the disease was endemic in 16 countries, including in West and Central Africa, Australia, Japan and French Guiana. https://www.nature.c...