This week's paper is by Daqi Li and Xiuxing Wang and team who show that tumour associated macrophages supply glioblastoma stem cells with lactate to promote their proliferation and induce KU70 lactylation to block cGAS-STING signalling and remodel the T…
RP @natcellbio.nature.com: ☕Li, Cui, Yang, Lu, Jiang, Zhang et al identify a lactate transport mechanism from tumor-associated #macrophages that regulates DNA repair and immune cell infiltration, which could be targeted to enhance #immunotherapy efficacy…
☕Li, Cui, Yang, Lu, Jiang, Zhang et al identify a lactate transport mechanism from tumor-associated #macrophages that regulates DNA repair and immune cell infiltration, which could be targeted to enhance #immunotherapy efficacy in #glioblastoma models. …
RRIDs were included in this paper. Thanks for making your methods matter! #methodsmatter #RRID #ReproducibleResearch