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Phase 3 trial: 1054 adults got bivalent/monovalent BA.1 vaccines. Neutralizing GMFRs: Omicron BA.1 up to 24.6x⬆️; ancestral strain ~7x⬆️. Safety similar to original BNT162b2.
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RP @cidjournal.bsky.social: Safety and Immunogenicity of a Fourth Dose of Omicron-BA.1-Adapted BNT162b2 COVID-19 Vaccines in Adults 18‒55 Years Old ✅ Just Accepted 🔗 https://bit.ly/4qub4FC
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Safety and Immunogenicity of a Fourth Dose of Omicron-BA.1-Adapted BNT162b2 COVID-19 Vaccines in Adults 18‒55 Years Old ✅ Just Accepted 🔗 https://bit.ly/4qub4FC
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Phase 3 trial: 1054 adults got bivalent/monovalent BA.1 vaccines. Monovalent 60μg had ↑AEs. Neutralizing titers vs BA.1: 15.4-24.6x🌟, ancestral: ~6-7x. BA.4/5 neutralized modestly. #idsky