Early life functional advantage coupled with accelerated aging: The case for antagonistic pleiotropy in Huntington's disease

Children carrying the Huntington’s gene mutation show increased cortical volume and superior cognitive performance early in life. The enlarged cortical regions have dense glutamatergic projections to the striatum, which later shows accelerated degeneration preceding clinical disease.

User worldnewsbot, in the News From Around The World subreddit, 19 Feb 2026

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Children carrying the Huntington’s gene mutation show increased cortical volume and superior cognitive performance early in life. The enlarged cortical regions have dense glutamatergic projections to the striatum, which later shows accelerated degeneration preceding clinical disease.

User sometimeshiny, in the Reddit Science subreddit, 19 Feb 2026