Amino acid-derived ionizable lipids enable inhaled base editing for therapeutic gene correction in the lung

Overview of attention for article published in Nature Materials, April 2026

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RP @natmater.nature.com: Amino acid-derived ionizable lipids enable inhaled base editing for therapeutic gene correction in the lung go.nature.com/4sbFlZZ

Amino acid-derived ionizable lipids enable inhaled base editing for therapeutic gene correction in the lung go.nature.com/4sbFlZZ

Our scientists developed an amino acid–based lipid nanoparticle, inhalable to deliver mRNA medicine into the lung. It has corrected cystic fibrosis mutations in preclinical models, opening routes to treat genetic lung diseases. Led by @BowenLi_Lab @UHN @…

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