Extremely preterm infants (EPT, <29 weeks' gestation) represent only 0.9% of births in the U.S., yet these infants are focus of most published research. Moderately preterm neonates (MPT, 29-33(6/7) weeks), are an understudied group of high-risk infants.
Objective: To determine the neonatal outcomes of MPT across the gestational age spectrum, and to compare these to EPT. A prospective observational cohort was formed in 18 Level 3-4 NICUs in the Eunice Kennedy Shriver NICHD Neonatal Research Network. Participants included all MPT admitted to NICUs, and all EPT born at sites between January 2012 and November 2013. Antenatal characteristics, and neonatal morbidities were abstracted from records using pre-specified definitions by trained neonatal research nurses.
MPT infants experienced morbidities similar to, although at lower rates, than EPT infants. The main cause of mortality was congenital malformation, accounting for 43% of deaths. CNS injury occurred including intraventricular hemorrhage. Most MPT required respiratory support but sequelae such as bronchopulmonary dysplasia were rare. The primary contributors to hospitalization beyond 36 weeks' gestation were inability to achieve adequate oral intake and persistent apnea.
MPT experience morbidity and prolonged hospitalization. Such morbidity deserves focused research to improve therapeutic and prevention strategies.Pediatric Research accepted article preview online, 18 April 2017. doi:10.1038/pr.2017.46.
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 August 2017.
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#20,080,916
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#4,465
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#190,232
of 352,268 outputs
Outputs of similar age from Pediatric Research
#34
of 97 outputs
Altmetric has tracked 32,999,168 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,222 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.9. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
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