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Purification, crystallization and preliminary X-ray analysis of IMP-18, a class B carbapenemase from Pseudomonas aeruginosa

Overview of attention for article published in Acta Crystallographica: Section F (International Union of Crystallography - IUCr), November 2013
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Article details
Title
Purification, crystallization and preliminary X-ray analysis of IMP-18, a class B carbapenemase from Pseudomonas aeruginosa
Published in
Acta Crystallographica: Section F (International Union of Crystallography - IUCr), November 2013
DOI 10.1107/s1744309113030480
Pubmed ID
Authors
Abstract

Class B β-lactamases are known as metallo-β-lactamases (MBLs) and they hydrolyze most β-lactams, including carbapenems. IMP-18, an MBL cloned from Pseudomonas aeruginosa, was overexpressed, purified and crystallized by vapour diffusion for X-ray crystallographic analysis. Preliminary X-ray analysis showed that the crystal diffracted to 2.4 Å resolution and belonged to the tetragonal space group P4(1)2(1)2, with unit-cell parameters a = b = 120.77, c = 96.54 Å, α = β = γ = 90°, suggesting the presence of two molecules in the asymmetric unit.

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Mendeley demographics

Mendeley demographics

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.
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Geographical breakdown

Geographical breakdown
Country Count As %
Romania 1 8%
Unknown 12 92%

Demographic breakdown

Readers by professional status
Readers by professional status Count As %
Student > Doctoral Student 3 23%
Student > Bachelor 2 15%
Professor 2 15%
Researcher 2 15%
Other 1 8%
Other 1 8%
Unknown 2 15%
Readers by discipline
Readers by discipline Count As %
Agricultural and Biological Sciences 3 23%
Biochemistry, Genetics and Molecular Biology 2 15%
Medicine and Dentistry 2 15%
Immunology and Microbiology 1 8%
Psychology 1 8%
Other 1 8%
Unknown 3 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 December 2013.
All research outputs
#28,598,653
of 34,357,314 outputs
Outputs from Acta Crystallographica: Section F (International Union of Crystallography - IUCr)
#488
of 545 outputs
Outputs of similar age
#308,122
of 377,967 outputs
Outputs of similar age from Acta Crystallographica: Section F (International Union of Crystallography - IUCr)
#6
of 11 outputs
Altmetric has tracked 34,357,314 research outputs across all sources so far. This one is in the 9th percentile – i.e., 9% of other outputs scored the same or lower than it.
So far Altmetric has tracked 545 research outputs from this source. They receive a mean Attention Score of 3.7. This one is in the 4th percentile – i.e., 4% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 377,967 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.