Title |
Emergence of NDM-1 Metallo-β-Lactamase in Pseudomonas aeruginosa Clinical Isolates from Serbia
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Published in |
Antimicrobial Agents and Chemotherapy, June 2011
|
DOI | 10.1128/aac.00226-11 |
Pubmed ID | |
Authors |
Branko Jovcic, Zorica Lepsanovic, Vesna Suljagic, Gorjana Rackov, Jelena Begovic, Ljubisa Topisirovic, Milan Kojic |
Abstract |
This work reports, for the first time, the presence of New Delhi metallo-β-lactamase 1 (NDM-1) in Pseudomonas aeruginosa. Moreover, this is the first report of the NDM-1 presence in the Balkan region. Cosmid gene libraries of carbapenem-nonsusceptible Pseudomonas aeruginosa clinical isolates MMA83 and MMA533 were screened for the presence of metallo-β-lactamases. Accordingly, both MMA83 and MMA533 carried the bla(NDM-1) gene. Pulsed-field gel electrophoresis (PFGE) analysis indicated that strains MMA83 and MMA533 belonged to different clonal groups. Five additional isolates from different patients clonally related to either MMA83 or MMA533 were found to be NDM-1 positive. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
South Africa | 1 | <1% |
Slovakia | 1 | <1% |
United States | 1 | <1% |
Philippines | 1 | <1% |
Poland | 1 | <1% |
Unknown | 125 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 24 | 18% |
Researcher | 21 | 16% |
Student > Master | 17 | 13% |
Student > Bachelor | 11 | 8% |
Student > Doctoral Student | 8 | 6% |
Other | 22 | 17% |
Unknown | 27 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 24 | 18% |
Medicine and Dentistry | 23 | 18% |
Immunology and Microbiology | 23 | 18% |
Biochemistry, Genetics and Molecular Biology | 13 | 10% |
Chemistry | 4 | 3% |
Other | 13 | 10% |
Unknown | 30 | 23% |