RP @uiowaphysiology.bsky.social: Congratulations to Dr. Ishita Chandel, Dr. Kevin Campbell, and the Campbell Lab on their new paper in Science! Their discovery uncovers a new way dystroglycan controls its own function, providing important insights into …
Fantastic from Ishita Chandel, graduate from my old department BioBio at Texas A&M https://bsky.app/profile/did:plc:vyrwozsjnc7szo6hoix5boej/post/3mt2ew5r4b22s
Dystroglycan holds its own keys by enzymatically trimming its binding sites, a self-regulating loop that ensures precise receptor function. 🧬 #ScienceMag https://www.science.org/doi/abs/10.1126/science.adz7427?af=R
I’m very excited to share my main postdoctoral work where we show that dystroglycan, a ubiquitous transmembrane receptor important for development, neuromuscular function and virus entry, regulates its own posttranslational modification by acting as a gly…