Effect of Cephalexin Plus Trimethoprim-Sulfamethoxazole vs Cephalexin Alone on Clinical Cure of Uncomplicated Cellulitis: A Randomized Clinical Trial

Overview of attention for article published in JAMA: Journal of the American Medical Association, May 2017

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RP @jonathanrydermd.bsky.social: For evidence, two RCTs show that addition of TMP-SMX to cephalexin has no benefit, so dual therapy not indicated: pubmed.ncbi.nlm.nih.gov/23457080/ pubmed.ncbi.nlm.nih.gov/28535235/ Nice systematic review from @stevento…

For evidence, two RCTs show that addition of TMP-SMX to cephalexin has no benefit, so dual therapy not indicated: pubmed.ncbi.nlm.nih.gov/23457080/ pubmed.ncbi.nlm.nih.gov/28535235/ Nice systematic review from @steventong.bsky.social on TMP-SMX for SST…

Looks like we can stop using bactrim for non-purulent skin infections: http://jamanetwork.com/journals/jama/fullarticle/2627970

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