RP @lynnbr2.bsky.social: Their studies support further investigation of TBK1 augmentation as a therapeutic strategy for preventing disease caused by UBQLN2 mutations. TBK1 overexpression reduces neuronal loss in the P497S UBQLN2 mouse model of ALS/FTD. …
Their studies support further investigation of TBK1 augmentation as a therapeutic strategy for preventing disease caused by UBQLN2 mutations. TBK1 overexpression reduces neuronal loss in the P497S UBQLN2 mouse model of ALS/FTD. www.sciencedirect.com/sc…
efforts directed toward increasing TBK1 expression may provide a therapeutic approach for treating ALS/FTD caused by UBQLN2 mutations. www.sciencedirect.com/science/arti...