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Mendeley readers
Attention Score in Context
| Title |
Inhibitory Effects of Apple Polyphenol on Induced Histamine Release from RBL-2H3 Cells and Rat Mast Cells
|
|---|---|
| Published in |
Nippon Nōgeikagaku Kaishi, May 2014
|
| DOI | 10.1271/bbb.62.1284 |
| Pubmed ID | |
| Authors |
Tomomasa KANDA, Hiroshi AKIYAMA, Akio YANAGIDA, Masayuki TANABE, GODA Yukihiro, Masatake TOYODA, Reiko TESHIMA, Yukio SAITO |
| Abstract |
The anti-allergic activities of polyphenol fractions extracted from immature fruits of apple (Rosaceae, Malus sp.) were evaluated by in vitro assays. A crude apple polyphenol (CAP) fraction, which had been obtained from the juice of immature apples by reverse-phase column chromatography, was further purified by LH-20 column chromatography to obtain an apple condensed tannin (ACT) fraction consisting of linear oligomeric epicatechins from the dimer to pentadecamer. ACT strongly inhibited the release of histamine from rat basophilic leukemia (RBL-2H3) cells stimulated by the antigen-stimulation and from rat peritoneal mast cells stimulated by compound 48/80. The IC50 values for histamine release were 30 micrograms/ml and 25 micrograms/ml, respectively. ACT also inhibited hyaluronidase activity and the increase in intracellular free calcium concentration in RBL-2H3 cells stimulated with the antigen. These results suggest that ACT affected early signal transduction including the calcium influx. |
Mendeley readers
The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | 2% |
| Unknown | 60 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 10 | 16% |
| Researcher | 10 | 16% |
| Student > Ph. D. Student | 7 | 11% |
| Student > Doctoral Student | 4 | 7% |
| Professor > Associate Professor | 4 | 7% |
| Other | 13 | 21% |
| Unknown | 13 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 22 | 36% |
| Medicine and Dentistry | 6 | 10% |
| Chemistry | 3 | 5% |
| Immunology and Microbiology | 3 | 5% |
| Nursing and Health Professions | 3 | 5% |
| Other | 8 | 13% |
| Unknown | 16 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 February 2013.
All research outputs
#5,583,444
of 25,850,671 outputs
Outputs from Nippon Nōgeikagaku Kaishi
#639
of 7,190 outputs
Outputs of similar age
#50,585
of 240,956 outputs
Outputs of similar age from Nippon Nōgeikagaku Kaishi
#379
of 2,823 outputs
Altmetric has tracked 25,850,671 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,190 research outputs from this source. They receive a mean Attention Score of 4.4. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 240,956 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 2,823 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.