microRNAs are short RNAs that reduce gene expression by binding to their targets. The accurate prediction of microRNA targets is essential to understanding the function of microRNAs. Computational predictions indicate that all human genes may be regulated by microRNAs, with each microRNA possibly targeting thousands of genes. Here we discuss computational methods for identifying mammalian microRNA targets and refining them for further experimental validation. We describe microRNA target prediction resources and procedures and how they integrate with various types of experimental techniques that aim to validate them or further explore their function. We also provide a list of target prediction databases and explain how these are curated.
Pharmacology, Toxicology and Pharmaceutical Science
2
3%
Other
2
3%
Unknown
7
11%
Attention Score in Context
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 February 2014.
All research outputs
#28,601,215
of 34,360,889 outputs
Outputs from Biochemical & Biophysical Research Communications
#28,508
of 33,075 outputs
Outputs of similar age
#306,435
of 379,806 outputs
Outputs of similar age from Biochemical & Biophysical Research Communications
#159
of 192 outputs
Altmetric has tracked 34,360,889 research outputs across all sources so far. This one is in the 9th percentile – i.e., 9% of other outputs scored the same or lower than it.
So far Altmetric has tracked 33,075 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one is in the 8th percentile – i.e., 8% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 379,806 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 192 others from the same source and published within six weeks on either side of this one. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.