| Title |
Birthweight and the risk of atopic diseases: the ISAAC Phase III study
|
|---|---|
| Published in |
Pediatric Allergy & Immunology, February 2014
|
| DOI | 10.1111/pai.12210 |
| Pubmed ID | |
| Authors |
Edwin A. Mitchell, Tadd Clayton, Luis García‐Marcos, Neil Pearce, Sunia Foliaki, Gary Wong, ISAAC Phase Three Study Group |
| Abstract |
The association between birthweight and asthma, eczema and rhinoconjunctivitisis conflicting. To examine the association between birthweight and symptoms of asthma, eczema and rhinoconjunctivitis. Parents or guardians of children aged 6–7 yr completed written questionnaires about symptoms of asthma, rhinoconjunctivitis and eczema, and several risk factors, including birthweight. There were 162,324 children from 60 centres in 26 countries. Low birthweight(<2.5 kg) was associated with an increased risk of symptoms of asthma (current wheeze odds ratio = 1.20; 95% confidence interval = 1.12–1.30). Low birthweight was associated with a lower risk of eczema ever. Low birthweight was not associated with rhinoconjunctivitis. Large babies (birthweight ≥4.5 kg) were not associated with any of these outcomes. This study has confirmed that low birthweight is a risk factor for symptoms of asthma, but not for rhinoconjunctivitis. The findings for eczema are equivocal. |
Login to access the Attention Digest and the Sentiment Analysis related to this output.
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 20% |
| Argentina | 1 | 20% |
| Canada | 1 | 20% |
| United States | 1 | 20% |
| Unknown | 1 | 20% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 80% |
| Scientists | 1 | 20% |
Mendeley demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 2% |
| Unknown | 60 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 10 | 16% |
| Student > Doctoral Student | 6 | 10% |
| Professor | 6 | 10% |
| Student > Ph. D. Student | 5 | 8% |
| Researcher | 5 | 8% |
| Other | 14 | 23% |
| Unknown | 15 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 28 | 46% |
| Nursing and Health Professions | 5 | 8% |
| Unspecified | 2 | 3% |
| Environmental Science | 2 | 3% |
| Agricultural and Biological Sciences | 2 | 3% |
| Other | 2 | 3% |
| Unknown | 20 | 33% |