Retinal Degenerative Diseases

Table of Contents

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   Book Overview
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   Chapter 1 Cell Type-Specific Epigenetic Signatures Accompany Late Stages of Mouse Retina Development
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   Chapter 2 Programmed Cell Death During Retinal Development of the Mouse Eye
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   Chapter 3 Spatial and Temporal Localization of Caveolin-1 Protein in the Developing Retina
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   Chapter 4 Glutathione S-Transferase Pi Isoform (GSTP1) Expression in Murine Retina Increases with Developmental Maturity
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   Chapter 5 RETINA-Specific Expression of Kcnv2 Is Controlled by Cone-Rod Homeobox (Crx) and Neural Retina Leucine Zipper (Nrl)
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   Chapter 6 AIPL1 Protein and its Indispensable Role in Cone Photoreceptor Function and Survival
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   Chapter 7 Primate Short-Wavelength Cones Share Molecular Markers with Rods
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   Chapter 8 Exploration of Cone Cyclic Nucleotide-Gated Channel-Interacting Proteins Using Affinity Purification and Mass Spectrometry
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    Chapter 9 Electrophysiological Characterization of Rod and Cone Responses in the Baboon Nonhuman Primate Model
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    Chapter 10 Animal Models, in “ The Quest to Decipher RPE Phagocytosis ”
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    Chapter 11 In Vivo and in Vitro Monitoring of Phagosome Maturation in Retinal Pigment Epithelium Cells
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    Chapter 12 Lack of Effect of Microfilament or Microtubule Cytoskeleton-Disrupting Agents on Restriction of Externalized Phosphatidylserine to Rod Photoreceptor Outer Segment Tips
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    Chapter 13 Retinal Degenerative Diseases
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    Chapter 14 Rescue of compromised lysosomes enhances degradation of photoreceptor outer segments and reduces lipofuscin-like autofluorescence in retinal pigmented epithelial cells.
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    Chapter 15 The Role of Bestrophin-1 in Intracellular Ca2+ Signaling
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    Chapter 16 Application of Next-Generation Sequencing to Identify Genes and Mutations Causing Autosomal Dominant Retinitis Pigmentosa (adRP).
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    Chapter 17 Digital Quantification of Goldmann Visual Fields (GVFs) as a Means for Genotype–Phenotype Comparisons and Detection of Progression in Retinal Degenerations
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    Chapter 18 Simplified System to Investigate Alteration of Retinal Neurons in Diabetes
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    Chapter 19 What is the Nature of the RGC-5 Cell Line?
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    Chapter 20 Modeling Retinal Dystrophies Using Patient-Derived Induced Pluripotent Stem Cells
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    Chapter 21 Retinal Degenerative Diseases
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    Chapter 22 IROme, a New High-Throughput Molecular Tool for the Diagnosis of Inherited Retinal Dystrophies-A Price Comparison with Sanger Sequencing.
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    Chapter 23 Genetic Heterogeneity and Clinical Outcome in a Swedish Family with Retinal Degeneration Caused by Mutations in CRB1 and ABCA4 Genes
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    Chapter 24 FAM161A, a Novel Centrosomal-Ciliary Protein Implicated in Autosomal Recessive Retinitis Pigmentosa
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    Chapter 25 Molecular Pathology of Macrophages and Interleukin-17 in Age-Related Macular Degeneration
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    Chapter 26 The Role of Monocytes and Macrophages in Age-Related Macular Degeneration
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    Chapter 27 Microglia in the aging retina.
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    Chapter 28 The Role of Complement Dysregulation in AMD Mouse Models.
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    Chapter 29 Prolonged Src Kinase Activation, a Mechanism to Turn Transient, Sublytic Complement Activation into a Sustained Pathological Condition in Retinal Pigment Epithelium Cells
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    Chapter 30 Inflammation in Age-Related Macular Degeneration
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    Chapter 31 Impairment of the Ubiquitin-Proteasome Pathway in RPE Alters the Expression of Inflammation Related Genes
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    Chapter 32 Retinal Degenerative Diseases
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    Chapter 33 Retinal Degenerative Diseases
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    Chapter 34 Should I Stay or Should I Go? Trafficking of Sub-Lytic MAC in the Retinal Pigment Epithelium
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    Chapter 35 Hypoxia-Inducible Factor (HIF)/Vascular Endothelial Growth Factor (VEGF) Signaling in the Retina.
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    Chapter 36 Is Age-Related Macular Degeneration a Microvascular Disease?
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    Chapter 37 Genetic Risk Models in Age-Related Macular Degeneration
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    Chapter 38 A Mechanistic Review of Cigarette Smoke and Age-Related Macular Degeneration
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    Chapter 39 Measuring Cone Density in a Japanese Macaque ( Macaca fuscata ) Model of Age-Related Macular Degeneration with Commercially Available Adaptive Optics
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    Chapter 40 Nuclear receptors as potential therapeutic targets for age-related macular degeneration.
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    Chapter 41 Utilizing Stem Cell-Derived RPE Cells as A Therapeutic Intervention for Age-Related Macular Degeneration
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    Chapter 42 Microglia-Müller Cell Interactions in the Retina
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    Chapter 43 Isolation and Ex Vivo Characterization of the Immunophenotype and Function of Microglia/Macrophage Populations in Normal Dog Retina
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    Chapter 44 Müller Cells and Microglia of the Mouse Eye React Throughout the Entire Retina in Response to the Procedure of an Intravitreal Injection
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    Chapter 45 Subretinal Infiltration of Monocyte Derived Cells and Complement Misregulation in Mice with AMD-Like Pathology
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    Chapter 46 Ambiguous Role of Glucocorticoids on Survival of Retinal Neurons
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    Chapter 47 Microglia-Müller Glia Crosstalk in the rd10 Mouse Model of Retinitis Pigmentosa
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    Chapter 48 The Neuroprotective Potential of Retinal Müller Glial Cells
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    Chapter 49 Leukemia Inhibitory Factor Signaling in Degenerating Retinas
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    Chapter 50 In Vivo Function of the ER-Golgi Transport Protein LMAN1 in Photoreceptor Homeostasis
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    Chapter 51 Investigating the Role of Retinal Müller Cells with Approaches in Genetics and Cell Biology
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    Chapter 52 An Overview of the Involvement of Interleukin-18 in Degenerative Retinopathies
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    Chapter 53 Chronic Intraocular Inflammation and Development of Retinal Degenerative Disease
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    Chapter 54 The relevance of chemokine signalling in modulating inherited and age-related retinal degenerations.
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    Chapter 55 The Complement Regulatory Protein CD59: Insights into Attenuation of Choroidal Neovascularization
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    Chapter 56 Regeneration-Associated Genes on Optic Nerve Regeneration in Fish Retina
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    Chapter 57 Dominant Stargardt Macular Dystrophy (STGD3) and ELOVL4
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    Chapter 58 Modulation of the Rate of Retinal Degeneration in T17M RHO Mice by Reprogramming the Unfolded Protein Response.
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    Chapter 59 Expression of Poly(ADP-Ribose) Glycohydrolase in Wild-Type and PARG-110 Knock-Out Retina
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    Chapter 60 Current Therapeutic Strategies for P23H RHO-Linked RP
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    Chapter 61 Pathogenesis of X-linked RP3: Insights from Animal Models
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    Chapter 62 Unc119 Gene Deletion Partially Rescues the GRK1 Transport Defect of Pde6d - /- Cones
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    Chapter 63 Retinal Function in Aging Homozygous Cln3 Δex7/8 Knock-In Mice
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    Chapter 64 Synergistic interaction of tubby and tubby-like protein 1 (tulp1).
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    Chapter 65 Interaction of Tubby-Like Protein-1 (Tulp1) and Microtubule-Associated Protein (MAP) 1A and MAP1B in the Mouse Retina
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    Chapter 66 CEP290 and the Primary Cilium
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    Chapter 67 Usher Syndrome Protein Network Functions in the Retina and their Relation to Other Retinal Ciliopathies.
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    Chapter 68 The Phenotype of the Good Effort Mutant Zebrafish is Retinal Degeneration by Cell Death and is Linked to the Chromosome Assembly Factor 1b Gene
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    Chapter 69 Knock-Down DHDDS Expression Induces Photoreceptor Degeneration in Zebrafish
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    Chapter 70 Spectral Domain Optical Coherence Tomography Findings in CNGB3-Associated Achromatopsia and Therapeutic Implications
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    Chapter 71 Photoreceptor Pathology in the X-Linked Retinoschisis (XLRS) Mouse Results in Delayed Rod Maturation and Impaired Light Driven Transducin Translocation
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    Chapter 72 Mouse Models for Cone Degeneration
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    Chapter 73 How Long Does a Photoreceptor Cell Take to Die? Implications for the Causative Cell Death Mechanisms
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    Chapter 74 Endoplasmic Reticulum Stress in Vertebrate Mutant Rhodopsin Models of Retinal Degeneration
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    Chapter 75 Bisretinoid Degradation and the Ubiquitin-Proteasome System
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    Chapter 76 Analysis of Mouse RPE Sheet Morphology Gives Discriminatory Categories
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    Chapter 77 High Glucose Activates ChREBP-Mediated HIF-1α and VEGF Expression in Human RPE Cells Under Normoxia
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    Chapter 78 Sphingolipids in Ocular Inflammation
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    Chapter 79 Biosynthesis of Very Long-Chain Polyunsaturated Fatty Acids in Hepatocytes Expressing ELOVL4
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    Chapter 80 Very Long Chain Polyunsaturated Fatty Acids and Rod Cell Structure and Function
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    Chapter 81 Oxidative Stress Regulation by DJ-1 in the Retinal Pigment Epithelium
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    Chapter 82 The Role of Reactive Oxygen Species in Ocular Malignancy
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    Chapter 83 The Effects of IRE1, ATF6, and PERK Signaling on adRP-Linked Rhodopsins
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    Chapter 84 Role of Endothelial Cell and Pericyte Dysfunction in Diabetic Retinopathy: Review of Techniques in Rodent Models
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    Chapter 85 Autophagy Induction Does Not Protect Retina Against Apoptosis in Ischemia/Reperfusion Model
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    Chapter 86 Advances in AAV Vector Development for Gene Therapy in the Retina
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    Chapter 87 Cone Specific Promoter for Use in Gene Therapy of Retinal Degenerative Diseases
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    Chapter 88 Episomal Maintenance of S/MAR-Containing Non-Viral Vectors for RPE-Based Diseases
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    Chapter 89 Gene Therapy in the Rd6 Mouse Model of Retinal Degeneration
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    Chapter 90 Gene Therapy for Stargardt Disease Associated with ABCA4 Gene.
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    Chapter 91 Assessment of Different Virus-Mediated Approaches for Retinal Gene Therapy of Usher 1B
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    Chapter 92 Gene Therapy Restores Vision and Delays Degeneration in the CNGB1 −/− Mouse Model of Retinitis Pigmentosa
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    Chapter 93 Therapy Strategies for Usher Syndrome Type 1C in the Retina
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    Chapter 94 Nipradilol Promotes Axon Regeneration Through S-Nitrosylation of PTEN in Retinal Ganglion Cells
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    Chapter 95 Reciprocal Changes in Factor XIII and Retinal Transglutaminase Expressions in the Fish Retina During Optic Nerve Regeneration
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    Chapter 96 N-acetylserotonin: circadian activation of the BDNF receptor and neuroprotection in the retina and brain.
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    Chapter 97 A High Content Screening Approach to Identify Molecules Neuroprotective for Photoreceptor Cells
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    Chapter 98 Antioxidant Therapy for Retinal Disease
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     Chapter 99 Pathophysilogical Mechanism and Treatment Strategies for Leber Congenital Amaurosis
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     Chapter 100 Retinal Degenerative Diseases
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     Chapter 101 Retinal Degenerative Diseases
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     Chapter 102 Pigment Epithelium-Derived Factor Protects Cone Photoreceptor-Derived 661W Cells from Light Damage Through Akt Activation
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     Chapter 103 Nanoceria as Bona Fide Catalytic Antioxidants in Medicine: What We Know and What We Want to Know…
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     Chapter 104 Nanoceria and Thioredoxin Regulate a Common Antioxidative Gene Network in tubby Mice.
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     Chapter 105 Intrascleral Transplantation of a Collagen Sheet with Cultured Brain-Derived Neurotrophic Factor Expressing Cells Partially Rescues the Retina from Damage due to Acute High Intraocular Pressure
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     Chapter 106 Neuroprotective Effects of Low Level Electrical Stimulation Therapy on Retinal Degeneration