| Title |
Carcinogenic and inflammatory effects of plutonium-nitrate retention in an exposed nuclear worker and beagle dogs
|
|---|---|
| Published in |
International Journal of Radiation Biology, November 2013
|
| DOI | 10.3109/09553002.2014.859765 |
| Pubmed ID | |
| Authors |
Christopher E. Nielsen, Xihai Wang, Robert J. Robinson, Antone L. Brooks, Jamie Lovaglio, Kristin M. Patton, Stacey L. McComish, Sergei Y. Tolmachev, William F. Morgan |
| Abstract |
Plutonium-nitrate has a moderately rapid translocation rate from the lung to blood stream. Previous studies have shown an unexpected retention of soluble plutonium in the beagles and human case studied here. The inflammatory responses that may be associated with long-term exposure to ionizing radiation were characterized. These pathways include tissue injury, apoptosis, and gene expression modifications. Other protein modifications related to carcinogenesis and inflammation and the various factors that may play a role in orchestrating complex interactions which influence tissue integrity following irradiation were investigated. |
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Mendeley demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 24 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 6 | 25% |
| Student > Master | 4 | 17% |
| Student > Bachelor | 2 | 8% |
| Professor | 2 | 8% |
| Researcher | 2 | 8% |
| Other | 2 | 8% |
| Unknown | 6 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 7 | 29% |
| Chemistry | 2 | 8% |
| Veterinary Science and Veterinary Medicine | 1 | 4% |
| Environmental Science | 1 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
| Other | 3 | 13% |
| Unknown | 9 | 38% |