| Title |
Influence of antiTNF-alpha antibody treatment on fracture healing under chronic inflammation
|
|---|---|
| Published in |
BMC Musculoskeletal Disorders, May 2014
|
| DOI | 10.1186/1471-2474-15-184 |
| Pubmed ID | |
| Authors |
Melanie Timmen, Heriburg Hidding, Britta Wieskötter, Wolfgang Baum, Thomas Pap, Michael J Raschke, Georg Schett, Jochen Zwerina, Richard Stange |
| Abstract |
The overexpression of tumor necrosis factor (TNF)-α leads to systemic as well as local loss of bone and cartilage and is also an important regulator during fracture healing. In this study, we investigate how TNF-α inhibition using a targeted monoclonal antibody affects fracture healing in a TNF-α driven animal model of human rheumatoid arthritis (RA) and elucidate the question whether enduring the anti TNF-α therapy after trauma is beneficial or not. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 51 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 11 | 22% |
| Student > Master | 6 | 12% |
| Researcher | 5 | 10% |
| Student > Doctoral Student | 4 | 8% |
| Other | 4 | 8% |
| Other | 10 | 20% |
| Unknown | 11 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 24 | 47% |
| Biochemistry, Genetics and Molecular Biology | 4 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 4% |
| Engineering | 2 | 4% |
| Chemical Engineering | 1 | 2% |
| Other | 4 | 8% |
| Unknown | 14 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 May 2014.
All research outputs
#17,721,395
of 22,756,196 outputs
Outputs from BMC Musculoskeletal Disorders
#2,890
of 4,037 outputs
Outputs of similar age
#155,043
of 226,522 outputs
Outputs of similar age from BMC Musculoskeletal Disorders
#65
of 102 outputs
Altmetric has tracked 22,756,196 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,037 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,522 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 102 others from the same source and published within six weeks on either side of this one. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.