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Enhancement of Carboplatin-Mediated Lung Cancer Cell Killing by Simultaneous Disruption of Glutathione and Thioredoxin Metabolism

Overview of attention for article published in Clinical Cancer Research, October 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (95th percentile)

Mentioned by

patent
42 patents

Readers on

mendeley
70 Mendeley
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Article details
Title
Enhancement of Carboplatin-Mediated Lung Cancer Cell Killing by Simultaneous Disruption of Glutathione and Thioredoxin Metabolism
Published in
Clinical Cancer Research, October 2011
DOI 10.1158/1078-0432.ccr-11-0736
Pubmed ID
Authors
Abstract

Cancer cells (relative to normal cells) show increased steady-state levels of hydroperoxides that are compensated by increased glucose and hydroperoxide metabolism. The current study determined whether inhibitors of glucose and hydroperoxide metabolism could induce chemoradiosensitization by enhancing oxidative stress in lung cancer cells.

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Mendeley demographics

Mendeley demographics

The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.
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Geographical breakdown

Geographical breakdown
Country Count As %
Malaysia 1 1%
United Kingdom 1 1%
Denmark 1 1%
Unknown 67 96%

Demographic breakdown

Readers by professional status
Readers by professional status Count As %
Researcher 12 17%
Student > Ph. D. Student 11 16%
Student > Bachelor 10 14%
Student > Master 6 9%
Professor > Associate Professor 6 9%
Other 10 14%
Unknown 15 21%
Readers by discipline
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 14 20%
Agricultural and Biological Sciences 14 20%
Medicine and Dentistry 8 11%
Chemistry 6 9%
Pharmacology, Toxicology and Pharmaceutical Science 3 4%
Other 6 9%
Unknown 19 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 21. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 February 2026.
All research outputs
#2,174,772
of 33,351,181 outputs
Outputs from Clinical Cancer Research
#1,650
of 17,376 outputs
Outputs of similar age
#9,376
of 176,513 outputs
Outputs of similar age from Clinical Cancer Research
#6
of 131 outputs
Altmetric has tracked 33,351,181 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 17,376 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.8. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 176,513 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 131 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.