The potential of a prebiotic oligosaccharide lactulose, a probiotic strain of Lactobacillus plantarum, or their synbiotic combination to control post-weaning colibacillosis in pigs were evaluated using an enterotoxigenic Escherichia coli (ETEC) K88 oral challenge. Seventy-two weanlings were fed four diets: a control diet (CTR), supplemented with L. plantarum (2 × 10(10) CFU ⋅ day(-1)) (LPN); with 10 g ⋅ kg(-1) lactulose (LAC) or a combination of both treatments (SYN). After 7 days the pigs were orally challenged. Six pigs per treatment were euthanized on days 6 and 10 post challenge (PC). Inclusion of lactulose improved the average daily gain (ADG) (P < 0.05), increased lactobacilli (P < 0.05) and the percentage of butyric acid (P < 0.02) in the colon. An increase in the ileum villous height (P < 0.05) and a reduction of the Pig Major Acute-phase Protein (Pig-MAP) in serum (P < 0.01) were observed also. The inclusion of the probiotic increased numbers of L. plantarum in the ileum and colon (P < 0.05) and in the total lactobacilli in the colon and trend to reduce diarrhoea (P = 0.09). The concentration of ammonia in ileal and colonic digesta was decreased (P < 0.05) and the villous height (P < 0.01) and ileal goblet cells (P < 0.05) increased at day 10 PC. A decrease in plasmatic TNF-α (P < 0.01) was also seen. Positive effects of both additives were combined in the SYN treatment resulting in a complementary synbiotic with potential to be used to control post-weaning colibacillosis.
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 February 2020.
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#8,261,140
of 25,371,288 outputs
Outputs from Applied and Environmental Microbiology
#8,059
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#76,304
of 242,853 outputs
Outputs of similar age from Applied and Environmental Microbiology
#59
of 148 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one has received more attention than most of these and is in the 66th percentile.
So far Altmetric has tracked 19,160 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.7. This one has gotten more attention than average, scoring higher than 57% of its peers.
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We're also able to compare this research output to 148 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.
