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Mendeley readers
| Title |
Phenolic profile, antioxidant, anti-inflammatory and cytotoxic activities of black (Tuber aestivum Vittad.) and white (Tuber magnatum Pico) truffles
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|---|---|
| Published in |
Food Chemistry, June 2014
|
| DOI | 10.1016/j.foodchem.2014.05.116 |
| Pubmed ID | |
| Authors |
Ivana N. Beara, Marija M. Lesjak, Dragana D. Četojević-Simin, Žaklina S. Marjanović, Jelena D. Ristić, Zorica O. Mrkonjić, Neda M. Mimica-Dukić |
| Abstract |
The aim of this study was a comprehensive investigation on phenolic profile, antioxidant, anti-inflammatory and cytotoxic activity of the still insufficiently explored black summer truffles (Tuber aestivum Vittad.) and white (Tuber magnatum Pico) truffles. Methanol and water extracts, obtained by maceration and Soxhlet extraction, were examined. Forty-five phenolics was studied using LC-MS/MS: presence of 14 compounds was confirmed, with the most dominant being p-hydroxybenzoic acid, baicalein and kaempferol (T. aestivum), epicatechin and catechin (T. magnatum). Moderate antioxidant activity of both species was determined through several assays. Only T. magnatum showed anti-inflammatory potential by inhibiting COX-1 and 12-LOX pathway products synthesis. Methanol extracts exerted cytotoxicity against some tumour cell lines (HeLa, MCF7, HT-29), besides the prominent activity of water extracts towards breast adenocarcinoma (MCF7). To conclude, these results support further investigations of phytochemicals and biological activity towards verification of nutraceutical use of both species. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 103 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Hungary | 2 | 2% |
| Iraq | 1 | <1% |
| Colombia | 1 | <1% |
| Unknown | 99 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 20 | 19% |
| Researcher | 18 | 17% |
| Student > Master | 17 | 17% |
| Student > Bachelor | 8 | 8% |
| Student > Postgraduate | 6 | 6% |
| Other | 11 | 11% |
| Unknown | 23 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 37 | 36% |
| Biochemistry, Genetics and Molecular Biology | 11 | 11% |
| Chemistry | 9 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 6% |
| Environmental Science | 4 | 4% |
| Other | 11 | 11% |
| Unknown | 25 | 24% |