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Large hypomethylated blocks as a universal defining epigenetic alteration in human solid tumors

Overview of attention for article published in Genome Medicine, August 2014
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (93rd percentile)

Mentioned by

news
3 news outlets
blogs
1 blog
twitter
2 X users
patent
7 patents
wikipedia
1 Wikipedia page

Readers on

mendeley
159 Mendeley
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Article details
Title
Large hypomethylated blocks as a universal defining epigenetic alteration in human solid tumors
Published in
Genome Medicine, August 2014
DOI 10.1186/s13073-014-0061-y
Pubmed ID
Authors
Abstract

One of the most provocative recent observations in cancer epigenetics is the discovery of large hypomethylated blocks, including single copy genes, in colorectal cancer, that correspond in location to heterochromatic LOCKs (large organized chromatin lysine-modifications) and LADs (lamin-associated domains).

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Timeline Attention over time Attention Score history
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Activity
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X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley demographics

Mendeley demographics

The data shown below were compiled from readership statistics for 159 Mendeley readers of this research output. Click here to see the associated Mendeley record.
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Geographical breakdown

Geographical breakdown
Country Count As %
United States 4 3%
United Kingdom 1 <1%
Germany 1 <1%
Brazil 1 <1%
Unknown 152 96%

Demographic breakdown

Readers by professional status
Readers by professional status Count As %
Student > Ph. D. Student 39 25%
Researcher 31 19%
Student > Master 12 8%
Student > Bachelor 8 5%
Student > Doctoral Student 7 4%
Other 21 13%
Unknown 41 26%
Readers by discipline
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 46 29%
Agricultural and Biological Sciences 37 23%
Medicine and Dentistry 10 6%
Computer Science 7 4%
Mathematics 4 3%
Other 11 7%
Unknown 44 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 49. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 July 2026.
All research outputs
#1,058,040
of 33,610,548 outputs
Outputs from Genome Medicine
#186
of 1,933 outputs
Outputs of similar age
#8,730
of 274,806 outputs
Outputs of similar age from Genome Medicine
#2
of 33 outputs
Altmetric has tracked 33,610,548 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,933 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.2. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 274,806 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.