It remains unclear whether if stereotactic radiosurgery (SRS) offers the same benefit for patients with type 2 trigeminal neuralgia (TN2) as for those with type 1 trigeminal neuralgia (TN1). The objective of this study is to compare the outcomes of patients with TN1 and TN2 following SRS.
SRS outcomes of trigeminal neuralgia patients treated at a single center from 1994 to 2016 were analyzed. Patients with TN1 were matched to those with TN2 in a 1:1 ratio based on sex, age, pre-treatment Barrow Neurological Institute (BNI) pain score, prior treatment, prior facial numbness, and maximum dose. The primary outcome was defined as a BNI pain score of ≤ 3.
The matched TN1 and TN2 cohorts were each comprised of 56 patients. There were no differences in BNI pain scores at last follow-up, new/worse facial numbness, or pain recurrence, or time to recurrence. Time to initial pain relief after SRS was longer for patients with TN2 (5.4 vs. 4.4 months; p=0.0016). Actuarial initial pain relief rates were 75%, 90%, and 90% for TN1, and 47%, 77% and 87% for TN2 at 5, 10, and 15 months, respectively. Actuarial pain relief maintenance rates were 72%, 67%, and 52% for TN1, and 53%, 32%, and 32% for TN2 at 1, 2, and 3 years, respectively.
SRS offers similar rates of initial pain relief, pain score distribution, pain recurrence and time to pain recurrence between TN1 and TN2 patients. The time to initial pain relief was longer for TN2 patients.
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 September 2017.
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