Energetic dissection of Gleevec's selectivity toward human tyrosine kinases

Overview of attention for article published in Nature Structural & Molecular Biology, September 2014

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In the top 25% of all research outputs scored by Altmetric
High Attention Score compared to outputs of the same age (94th percentile)
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@davidlmobley @fraser_lab anticancer drug Gleevec binding to Abl kinase https://t.co/wZOWUmpfWi

RT @benjaminbarad @fraser_lab. How Src & Abl adpot similar structures bound to Gleevec but show different affinities? http://t.co/j8oFfh5Swm

.@fraser_lab Abl kinase combines conformational selection with induced fit for Gleevec binding. http://t.co/JYOtWB4hRI #fljcnlt

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