| Title |
Active immunotherapy using dendritic cells in the treatment of glioblastoma multiforme
|
|---|---|
| Published in |
Cancer Treatment Reviews, June 2013
|
| DOI | 10.1016/j.ctrv.2013.05.007 |
| Pubmed ID | |
| Authors |
Amade Bregy, Theresa M. Wong, Ashish H. Shah, John M. Goldberg, Ricardo J. Komotar |
| Abstract |
Glioblastoma multiforme, the most common malignant brain tumor still has a dismal prognosis with conventional treatment. Therefore, it is necessary to explore new and/or adjuvant treatment options to improve patient outcomes. Active immunotherapy is a new area of research that may be a successful treatment option. The focus is on vaccines that consist of antigen presenting cells (APCs) loaded with tumor antigen. We have conducted a systematic review of prospective studies, case reports and clinical trials. The goal of this study was to examine the efficacy and safety in terms of complications, median overall survival (OS), progression free survival (PFS) and quality of life. |
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X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Portugal | 1 | <1% |
| Netherlands | 1 | <1% |
| Italy | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 102 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 21 | 20% |
| Student > Bachelor | 19 | 18% |
| Student > Master | 13 | 12% |
| Other | 8 | 7% |
| Student > Postgraduate | 7 | 7% |
| Other | 18 | 17% |
| Unknown | 21 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 36 | 34% |
| Agricultural and Biological Sciences | 23 | 21% |
| Biochemistry, Genetics and Molecular Biology | 7 | 7% |
| Neuroscience | 5 | 5% |
| Immunology and Microbiology | 3 | 3% |
| Other | 6 | 6% |
| Unknown | 27 | 25% |