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Tunable dynamics of microtubule-based active isotropic gels

Overview of attention for article published in Philosophical Transactions of the Royal Society A: Mathematical, Physical & Engineering Sciences, November 2014
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Article details
Title
Tunable dynamics of microtubule-based active isotropic gels
Published in
Philosophical Transactions of the Royal Society A: Mathematical, Physical & Engineering Sciences, November 2014
DOI 10.1098/rsta.2014.0142
Pubmed ID
Authors
Abstract

We investigate the dynamics of an active gel of bundled microtubules (MTs) that is driven by clusters of kinesin molecular motors. Upon the addition of ATP, the coordinated action of thousands of molecular motors drives the gel to a highly dynamical turbulent-like state that persists for hours and is only limited by the stability of constituent proteins and the availability of the chemical fuel. We characterize how enhanced transport and emergent macroscopic flows of active gels depend on relevant molecular parameters, including ATP, kinesin motor and depletant concentrations, MT volume fraction, as well as the stoichiometry of the constituent motor clusters. Our results show that the dynamical and structural properties of MT-based active gels are highly tunable. They also indicate existence of an optimal concentration of molecular motors that maximize far-from-equilibrium activity of active isotropic MT gels.

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X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley demographics

Mendeley demographics

The data shown below were compiled from readership statistics for 120 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Geographical breakdown
Country Count As %
United States 3 3%
Spain 2 2%
Vietnam 1 <1%
Japan 1 <1%
United Kingdom 1 <1%
France 1 <1%
Germany 1 <1%
Unknown 110 92%

Demographic breakdown

Readers by professional status
Readers by professional status Count As %
Student > Ph. D. Student 38 32%
Researcher 18 15%
Student > Master 11 9%
Professor 7 6%
Student > Bachelor 6 5%
Other 16 13%
Unknown 24 20%
Readers by discipline
Readers by discipline Count As %
Physics and Astronomy 53 44%
Agricultural and Biological Sciences 12 10%
Engineering 11 9%
Biochemistry, Genetics and Molecular Biology 7 6%
Chemistry 5 4%
Other 9 8%
Unknown 23 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 October 2014.
All research outputs
#27,742,719
of 34,377,743 outputs
Outputs from Philosophical Transactions of the Royal Society A: Mathematical, Physical & Engineering Sciences
#2,938
of 3,607 outputs
Outputs of similar age
#323,094
of 423,161 outputs
Outputs of similar age from Philosophical Transactions of the Royal Society A: Mathematical, Physical & Engineering Sciences
#34
of 49 outputs
Altmetric has tracked 34,377,743 research outputs across all sources so far. This one is in the 16th percentile – i.e., 16% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,607 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.8. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 423,161 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 49 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.