| Title |
DNA Methylation in Social Insects: How Epigenetics Can Control Behavior and Longevity
|
|---|---|
| Published in |
Annual Review of Entomology, October 2014
|
| DOI | 10.1146/annurev-ento-010814-020803 |
| Pubmed ID | |
| Authors | |
| Abstract |
In eusocial insects, genetically identical individuals can exhibit striking differences in behavior and longevity. The molecular basis of such phenotypic plasticity is of great interest to the scientific community. DNA methylation, as well as other epigenetic signals, plays an important role in modulating gene expression and can therefore establish, sustain, and alter organism-level phenotypes, including behavior and life span. Unlike DNA methylation in mammals, DNA methylation in insects, including eusocial insects, is enriched in gene bodies of actively expressed genes. Recent investigations have revealed the important role of gene body methylation in regulating gene expression in response to intrinsic and environmental factors. In this review, we summarize recent advances in DNA methylation research and discuss its significance in our understanding of the epigenetic underpinnings of behavior and longevity. Expected final online publication date for the Annual Review of Entomology Volume 60 is January 07, 2014. Please see http://www.annualreviews.org/catalog/pubdates.aspx for revised estimates. |
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 20% |
| France | 1 | 20% |
| United States | 1 | 20% |
| Unknown | 2 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 100% |
Mendeley demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 1% |
| Germany | 2 | <1% |
| Brazil | 2 | <1% |
| South Africa | 1 | <1% |
| New Zealand | 1 | <1% |
| France | 1 | <1% |
| Switzerland | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 407 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 91 | 22% |
| Researcher | 65 | 15% |
| Student > Master | 57 | 14% |
| Student > Bachelor | 48 | 11% |
| Professor > Associate Professor | 21 | 5% |
| Other | 67 | 16% |
| Unknown | 72 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 213 | 51% |
| Biochemistry, Genetics and Molecular Biology | 77 | 18% |
| Neuroscience | 9 | 2% |
| Environmental Science | 9 | 2% |
| Medicine and Dentistry | 8 | 2% |
| Other | 16 | 4% |
| Unknown | 89 | 21% |