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Acute Targeting of General Transcription Factor IIB Restricts Cardiac Hypertrophy via Selective Inhibition of Gene Transcription

Overview of attention for article published in Circulation: Heart Failure, November 2014
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17 Mendeley
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Article details
Title
Acute Targeting of General Transcription Factor IIB Restricts Cardiac Hypertrophy via Selective Inhibition of Gene Transcription
Published in
Circulation: Heart Failure, November 2014
DOI 10.1161/circheartfailure.114.001660
Pubmed ID
Authors
Abstract

-We previously reported that specialized and housekeeping genes are differentially regulated via de novo recruitment and pause-release of RNA polymerase II (pol II), respectively, during cardiac hypertrophy. However, the significance of this finding remains to be examined. Therefore, the purpose of this study was to determine the mechanisms that differentially regulate these gene groups and exploit them for therapeutic targeting.

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Timeline Attention over time Attention Score history
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X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley demographics

Mendeley demographics

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.
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Geographical breakdown

Geographical breakdown
Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status
Readers by professional status Count As %
Researcher 5 29%
Student > Doctoral Student 2 12%
Student > Ph. D. Student 2 12%
Other 1 6%
Student > Bachelor 1 6%
Other 2 12%
Unknown 4 24%
Readers by discipline
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 24%
Medicine and Dentistry 3 18%
Pharmacology, Toxicology and Pharmaceutical Science 1 6%
Agricultural and Biological Sciences 1 6%
Sports and Recreations 1 6%
Other 1 6%
Unknown 6 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 November 2014.
All research outputs
#24,622,233
of 27,359,965 outputs
Outputs from Circulation: Heart Failure
#1,631
of 1,717 outputs
Outputs of similar age
#234,360
of 272,356 outputs
Outputs of similar age from Circulation: Heart Failure
#27
of 28 outputs
Altmetric has tracked 27,359,965 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,717 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 272,356 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.