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@SatishPatel_Cam @NatMetabolism @uiowa A quick example: physiological FGF21 levels are rapidly cleared in mice when transitioning between metabolic states (from fast to refeed). https://t.co/d5Z1XiL4E8
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@DanielJDrucker @IntJObesity I don’t know how his sub field very well, but how strong are the mouse data? Has the equivalent experiment been done? Just looked up the AdipoQ-Cre Fgf21 KO mouse and it’s seems to support no role https://t.co/SZfVukRj7n