Vitiligo is a disease of cutaneous pigment cells. Recently we reported that one third of patients with vitiligo had destructive lesions in the retinal pigment epithelium and/or the choroid which were visible by ophthalmologic examination. To determine whether abnormalities of the pigment system of the eye and skin are in fact associated, we examined for vitiligo the skin and hair of 107 patients with active uveitis. Thirty-four patients had an infectious or a known cause for their uveitis and none of these had vitiligo. In contrast, six of seventy-three patients (8%) with idiopathic uveitis had vitiligo or early graying of the hair. Seven other patients with active inflammatory diseases of the ocular pigment system were referred for evaluation of white spots on the skin. One of these patients was legally blind (correlated visual acuity less than 20/200 in both eyes) due to chorioretinal scars in the fovea. The finding that vitiligo is more common than expected in patients with uveitis is significant biologically and statistically. This observation supports our hypothesis that the same systemic factors, probably immunologic, are responsible for destroying pigment cells in the skin (vitiligo) and the eye (uveitis).
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 November 2022.
All research outputs
#6,093,467
of 32,209,097 outputs
Outputs from Journal of the American Academy of Dermatology
#3,786
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Outputs of similar age
#1,099
of 9,446 outputs
Outputs of similar age from Journal of the American Academy of Dermatology
#3
of 15 outputs
Altmetric has tracked 32,209,097 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 12,991 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.3. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 9,446 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.
