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Significance of isomerization in hydroxocobalamin

Overview of attention for article published in Biochemical & Biophysical Research Communications, December 1984
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Article details
Title
Significance of isomerization in hydroxocobalamin
Published in
Biochemical & Biophysical Research Communications, December 1984
DOI 10.1016/0006-291x(84)90595-3
Pubmed ID
Authors
Abstract

Hydroxocobalamin is present in fairly large proportions both in foods and in the human body and apparently plays an important biological role. Since cyanocobalamin seems to play hardly any significant biochemical role in healthy humans, several physicians prefer to administer hydroxocobalamin to vitamin B12 deficient patients. We find that hydroxocobalamin in solution isomerizes very readily at room and lower temperatures. Our observations raise the question whether "Mother Nature" has gone awry in using an easily convertible substance like hydroxocobalamin or that the new isomeric forms play some significant role. These observations may also have a bearing on the reported occurrence of unidentified corrinoids in animal tissues, human red cells, liver and brain.

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Mendeley demographics

Mendeley demographics

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.
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Geographical breakdown

Geographical breakdown
Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status
Readers by professional status Count As %
Student > Master 3 38%
Professor > Associate Professor 1 13%
Researcher 1 13%
Student > Doctoral Student 1 13%
Unknown 2 25%
Readers by discipline
Readers by discipline Count As %
Psychology 3 38%
Nursing and Health Professions 2 25%
Pharmacology, Toxicology and Pharmaceutical Science 1 13%
Unknown 2 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 December 2014.
All research outputs
#24,756,003
of 34,363,559 outputs
Outputs from Biochemical & Biophysical Research Communications
#26,774
of 33,077 outputs
Outputs of similar age
#43,056
of 52,680 outputs
Outputs of similar age from Biochemical & Biophysical Research Communications
#94
of 95 outputs
Altmetric has tracked 34,363,559 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 33,077 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 52,680 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 3rd percentile – i.e., 3% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 95 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.