Different tail enigneered resorcinarenes have been examined towards the insulin fibrillation via experimental and computational studies. The resorcinarene showed a promising effect on the inhibition of insulin fibrillalition via ThT assay, CD spectra, and AFM images. Both ThT assay and computational results indicate the tail from the resorcinarene has an impact on insulin fibrillation by either inhibition or promotion because of the resident position on insulin. These observations have significant biological implications in the design of lead drug molecules as well as the development of potential therapeutic strategies.
Pharmacology, Toxicology and Pharmaceutical Science
1
7%
Biochemistry, Genetics and Molecular Biology
1
7%
Materials Science
1
7%
Other
0
0%
Unknown
5
33%
Attention Score in Context
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 December 2017.
All research outputs
#31,270,447
of 34,457,357 outputs
Outputs from Chemistry - A European Journal
#25,178
of 29,599 outputs
Outputs of similar age
#438,079
of 492,787 outputs
Outputs of similar age from Chemistry - A European Journal
#489
of 689 outputs
Altmetric has tracked 34,457,357 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 29,599 research outputs from this source. They receive a mean Attention Score of 4.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 689 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.