Background: Recent evidence has suggested links between obesity and outcomes for various types of cancer. This study investigates the impact that body composition has on survival in patients with head and neck cancer. Methods: Data prospectively collected from 578 patients were analyzed using Cox regression models to determine independent associations that pretreatment body mass index (BMI) and 3-month weight change have on observed survival. Results: Higher BMIs were associated with better survival (p<.001). Five-year rates ranged from 33.8% for underweight to 75.3% for overweight/obese patients. Patients with stable weight had the highest 5-year rate (72.6%; p=.019), while patients who gained ≥5% had worse survival (45.8%) than those who lost ≥5% (65.8%). BMI independently predicted survival, while weight change was not an independent predictor. Conclusions: This demonstrated association between BMI and survival provides useful information when offering prognoses and investigating optimal treatments. This article is protected by copyright. All rights reserved.
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 December 2014.
All research outputs
#19,864,135
of 24,411,829 outputs
Outputs from Head & Neck
#2,594
of 3,877 outputs
Outputs of similar age
#195,086
of 267,956 outputs
Outputs of similar age from Head & Neck
#72
of 176 outputs
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