Introduction: The emergence of multidrug-resistant (MDR) infections has been extensively observed worldwide and has become a priority issue over past decade. Tigecycline , a broad spectrum antibiotic covering against many MDR organisms, has been widely used. However, recent meta-analysis studies have raised a concern for its efficacy and safety. Reviewing tigecycline safety data would enhance the appropriate use of this medication. Areas covered: This article reviews the safety profile of tigecycline, including its side effects and drug interactions. Expert opinion: The increased mortality associated with tigecycline is not yet well understood. Based on current evidence, alternative options must be prioritized over tigecycline if available. When tigecycline use is warranted, vigilant observation to identify any breakthrough infections and careful monitoring of progression of the original infection are highly recommended. Considering a second agent (either for synergism or enhancing coverage) may be required.
Pharmacology, Toxicology and Pharmaceutical Science
8
8%
Agricultural and Biological Sciences
8
8%
Immunology and Microbiology
8
8%
Biochemistry, Genetics and Molecular Biology
7
7%
Other
8
8%
Unknown
30
31%
Attention Score in Context
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 November 2024.
All research outputs
#5,640,508
of 26,823,206 outputs
Outputs from Expert Opinion on Drug Safety
#244
of 1,326 outputs
Outputs of similar age
#69,997
of 364,939 outputs
Outputs of similar age from Expert Opinion on Drug Safety
#9
of 28 outputs
Altmetric has tracked 26,823,206 research outputs across all sources so far. Compared to these this one has done well and is in the 78th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,326 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 364,939 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
